Growth hormone-releasing factor analogs

Details Growth hormone-releasing factor analogs Growth hormone-releasing factor analogs

1990-05-21

1991-09-24

Doll, John

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

514 12, 514963, 514965, 530324, A61K 3743, C07K 710

Patent

active

RE0336998

ABSTRACT:
Human Growth Hormone-Releasing Factor (hGRF) analogs having the sequence [X.sup.3, Y.sup.8, Z.sup.25, Nle.sup.27 ]-hGRF(1-A)--B, wherein X, Y and Z are selected from the group consisting of Asn and Asp, A has a value from 29-44, and B is NH.sub.2 or OH are synthesized and administered to animals to stimulate the release of Growth Hormone (GH).

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