Growth hormone releasing factor analogs

Details Growth hormone releasing factor analogs Growth hormone releasing factor analogs

1985-08-06

1987-03-10

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 13, 530324, 530325, A61K 3736, A61K 3724, C07K 710

Patent

active

046491317

ABSTRACT:
Novel growth hormone releasing factor analogs in which glycine at position 15 is replaced by appropriately selected amino acids demonstrate enhanced potency for the release of growth hormone and the analogs can be administered to a subject having a deficiency of growth hormone.

REFERENCES:
patent: 4529595 (1985-07-01), Rivier et al.
patent: 4562175 (1985-12-01), Chang et al.
Hruby, V. J. and D. H. Rich, editors, Peptides Structure and Function, pp. 853-856 (198), Pierce Chemical Co., Rockford, Ill.
Ling, et al., Biochemical and Biophysical Research Communications, 123:854-861, 1984.
Rivier, et al, Letters to Nature, 300:276-278; 1982.
Guillemin, et al., Science, 218:585-587; 1982.

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