Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.
Patent
1994-01-12
1995-01-31
Schain, Howard E.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Tripeptides, e.g., tripeptide thyroliberin , etc.
530345, 525 541, A61K 3702, A61L 2700
Patent
active
053860128
ABSTRACT:
This invention utilizes the biological activity of the copper complex of the tripeptide glycyl-L-histidyl-L-lysine. This peptide is covalently bound to artificial implants where it has a chemoattractive effect and also acts when it is released by hydrolysis of the implants. The peptide increases fibroblastic collagen synthesis thereby enabling a more rapid replacement of the implants with human tissue.
REFERENCES:
patent: 4584284 (1986-04-01), Audhya et al.
patent: 4665054 (1987-05-01), Pickart
patent: 4767753 (1988-08-01), Pickart
patent: 4810693 (1989-03-01), Pickart
patent: 4877770 (1989-10-01), Pickart
patent: 4882162 (1989-11-01), Ikada et al.
patent: 5059588 (1991-10-01), Pickart
Prickril Benet
Schain Howard E.
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