Growth-enhancing cystamine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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564 30, 564 34, 564 33, 564 59, 564 94, 564 98, 564 99, 564104, 564108, 564186, 564500, 260465D, 514588, 514580, 514609, 514610, 514482, 514483, 514526, 514528, 514590, 514616, 514602, 514604, 514605, 560231, C07C14374, C07C14378, A61K 3118

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045686947

ABSTRACT:
Cystamine derivatives of the formula: ##STR1## [wherein n represents 2 or 3, R.sup.1 and R.sup.2 each represents a hydrogen atom, or an alkyl group optionally substituted by a hydroxy, amino, alkylamino or dialkylamino group, or represents a cycloalkyl or aryl group, and X.sup.1 represents a group selected from the formulae .dbd.N--CN, .dbd.N--NO.sub.2, .dbd.N--COR.sup.3, .dbd.N--COOR.sup.3, .dbd.N--NH--CONH.sub.2, .dbd.N--SO.sub.2 R.sup.3, .dbd.CH--NO.sub.2, .dbd.CH--SO.sub.2 R.sup.3, .dbd.C(CN).sub.2, .dbd.C(CN)COOR.sup.3 and .dbd.C(CN)CONH.sub.2 (wherein R.sup.3 represents an alkyl or aryl group), or R.sup.1 represents a hydrogen atom, R.sup.2 represents an alkyl group optionally substituted by a hydroxy, amino, alkylamino or dialkylamino group, or represents a cycloalkyl or aryl group and X.sup.1 represents an oxygen or sulphur atom] have been found to be useful in the promotion of the growth of non-human animals including birds.
Prcesses for the preparation of the cystamine derivatives and compositions containing them for administration to non-human animals are described.

REFERENCES:
patent: 3428576 (1969-02-01), Dickinson et al.
patent: 4157340 (1979-06-01), Crenshaw et al.
patent: 4314076 (1982-02-01), Oiry et al.
Kalopissis et al., CA 71: 101308c, (1969).
Kalopissis et al., CA 76: 103626g, (1972).

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