Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1994-08-12
2000-09-19
Ulm, John
Drug, bio-affecting and body treating compositions
Lymphokine
530351, 536 231, 536 235, 536 243, 536 2431, 514 2, 514 8, 514 12, 435 695, 435325, 435471, 4352523, 4353201, A61K 3819, C07K 14495, C12N 1519
Patent
active
061207608
ABSTRACT:
The invention provides DNA sequences encoding novel members of the TGF-.beta. family of proteins. The TGF-.beta. family comprises proteins which function as growth and/or differentiation factors and which are useful in medical applications. Accordingly, the invention also describes the isolation of the above-mentioned DNA sequences, the expression of the encoded proteins, the production of the proteins and pharmaceutical compositions containing the proteins.
REFERENCES:
patent: 5801014 (1998-09-01), Lee et al.
Chang et al. (1994). J. Biol. Chem. vol. 269, No. 45, pp. 28227-28234.
Hotten et al., "Cloning of a New Member of the TGF-.beta. Family: A Putative New Activin .beta..sub.C Chain", Biochem. & Biophys. Res. Comm., vol. 206, No. 2, 1995.
Bechtold Rolf
Hotten Gertrud
Neidhardt Helge
Pohl Jens
Biopharm Gesellschaft zur Biotechnologischen Entwicklung
Mertz Prema
Ulm John
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