Growth differentiation factor, lefty-2

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S007210

Reexamination Certificate

active

10684209

ABSTRACT:
Growth differentiation factor, Lefty-2, is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the Lefty-2 polypeptide and polynucleotide sequences.

REFERENCES:
patent: 5194596 (1993-03-01), Tischer et al.
patent: 5350836 (1994-09-01), Kopchick et al.
Beddington, Rosa, “Left, Right, Left . . . Turn,” Nature 381:116-117, 1996.
Kosaki, K., et al., “Characterization and Mutation Analysis of HumanLEFTY AandLEFTY B, Homologues of Murine Genes Implicated in Left-Right Axis Development,” Am. J. Hum. Genet. 64:712-721, 1999.
Kothapalli, Ravi et al., “Detection ofebaf, a Novel Human Gene of the Transforming Growth Factor β Superfamily,” J. Clin. Invest. 99:(10)2342-2350, 1997.
Meno, Chikara et al., “Left-Right Asymmetric Expression of the TGFβ-Family Memberleftyin Mouse Embryos,” Nature 381:151-155, 1996.
Meno, Chikara et al., “Lefty-1Is Required for Left-Right Determination as a Regulator oflefty-2andnodal,” Cell 94:287-297, 1998.
Schlange, Thomas et al., “Chick CFC Controls Lefty1 Expression in the Embryonic Midline and Noda Expression in the Lateral Plate,” Developmental Biology 234:376-389, 2001.
Yoshioka, Hidefumi et al., “Pitx2, a Bicoid-Type Homeobox Gene, Is Involved in a Lefty-Signaling Pathway in Determination of Left-Right Asymmetry,” Cell 94:299-305, 1998.
Benjamin et al., 1998, Development 125:1591-1598.
Vukicevic et al., 1996, PNAS USA 93:9021-9026.
Massague, 1987, Cell 49:437-438.
Pilbeam et al., 1993, Bone 14:717-720.
Skolnick et al., 2000, Trends in Biotech. 18:34-39.
Bork, 2000, Genome Research 10:398-400.
Doerks et al., 1998, Trends in Genetics 14:248-250.
Smith et al., 1997, Nature Biotechnology 15:1222-1223.
Brenner, 1999, Trends in Genetics 15:132-133.
Bork, 1998, Trends in Genetics 12:425-427.
Wells, 1990, Biochemistry 29:8509-8517.
Ngo et al., 1994, The Protein Folding Problem and Tertiary Structure Prediction, Merz et al., eds., Birkhauser, Boston, pp. 492-495.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Growth differentiation factor, lefty-2 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Growth differentiation factor, lefty-2, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Growth differentiation factor, lefty-2 will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3744086

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.