Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Reexamination Certificate
2007-04-03
2007-04-03
Romeo, David (Department: 1647)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
C424S158100, C424S178100, C435S007230, C435S007900, C530S388230, C530S389200, C530S391100, C530S391300
Reexamination Certificate
active
09880708
ABSTRACT:
Growth differentiation factor-5 (GDF-5) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-5 polypeptide and polynucleotide sequences.
REFERENCES:
patent: 4741998 (1988-05-01), Herr et al.
patent: 5061786 (1991-10-01), Burnier et al.
patent: WO 93/16099 (1993-08-01), None
Nathan et al. Cytokines in context. Journal of Cell Biology, (Jun. 1991) 113 (5) 981-986.
Hill et al. Bi-functional action of transforming growth factor-beta on DNA synthesis in early passage human fetal fibroblasts. J Cell Physiol Aug. 1986;128(2):322-8.
Bowie et al., “Deciphering the message in protein sequences: Tolerance to amino acid substitutions,”Science247:1306-1310 (1990).
Daniel et al.,Virology202(2):540-549 (1994).
Lee, “Identification of a novel member (GDF-1) of the transforming growth factor-beta superfamily,”Molecular Endocrinology4(7):1034-1040 (1990).
Wang et al., “Recombinant human bone morphogenetic protein induces bone formation,”Proc. Natl. Acad. Sci. USA87(6):2220-2224 (1990).
Wozney et al., “Novel regulators of bone formation: molecular clones and activities,”Science242:1528-1534 (1988).
Huynh Thanh
Lee Se-Jin
DLA Piper (US) LLP
Romeo David
The Johns Hopkins University School of Medicine
LandOfFree
Growth differentiation factor-5 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Growth differentiation factor-5, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Growth differentiation factor-5 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3737148