Growth differentiation factor-16

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Details

C435S069100, C435S320100, C435S235100

Reexamination Certificate

active

07098323

ABSTRACT:
Growth differentiation factor-16 (GDF-16) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diganostic and therapeutic methods of using the GDF-16 polypeptide and polynucleotide sequences.

REFERENCES:
patent: 5916751 (1999-06-01), Tabibzadeh et al.
patent: 6027917 (2000-02-01), Celeste et al.
Tabibzadeh et al., Accession No. U81523, May 1997.
Massagué J. Ann. Rev. Biochem., 1998, vol. 67, pp. 753-791.
Kothapalli, Ravi et al., “Detection of ebaf, a Novel Human Gene of the Transforming Growth Factor β Superfamily”,The American Society for Clinical Investigation, Inc., vol. 99, No. 10, pp. 2342-2350, 1997.
Tabibzadeh, Siamak et al., “Distinct Tumor Specific Expression of TGFB4 (ebaf)*, a Novel Human Gene of the TGF-β Superfamily”,Frontiers in Bioscience 2, 1-18, 1997.

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