Growth differentiation factor-11 transgenic mice

Details Growth differentiation factor-11 transgenic mice Growth differentiation factor-11 transgenic mice

1997-02-06

1999-12-28

Crouch, Deborah

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

Transgenic nonhuman animal

800 21, 800 22, 800 25, 435455, 435463, 4353201, 435325, C12N 1509, C12N 1500, C12N 1563, C12N 500

Patent

active

060084340

ABSTRACT:
A transgenic mouse whose genome comprises a disruption of the endogenous growth differentiation factor-11 (GDF-11) gene is disclosed. Also disclosed are methods for making such mice. The mice exhibit a phenotype of increased muscle tissue.

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