Growth arrest homeobox gene

Details Growth arrest homeobox gene Growth arrest homeobox gene

2005-05-24

2005-05-24

Hutson, Richard (Department: 1652)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S069100, C536S023100, C536S023500, C536S023200, C530S399000, C530S358000

Reexamination Certificate

active

06897293

ABSTRACT:
A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.

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GenBank Database, Accession No.: 216406 mouse Mox-2A submitted by A.F. Candia to GenBank and created on Oct. 5, 1992.
Mouse Mox-2 sequence on Mar. 6, 1993 GenBank Database, Accession No.: 216406.

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