Growth arrest homebox gene

Details Growth arrest homebox gene Growth arrest homebox gene

2006-08-01

2006-08-01

Saoud, Christine J. (Department: 1647)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S243000, C435S320100, C435S325000, C536S023500

Reissue Patent

active

RE039219

ABSTRACT:
A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.

REFERENCES:
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Gene sequence for Mox-1 (2182 base pairs, designated Mox-2) submitted by A. F. Candia to New GenBank and created on Sep. 25, 1992.
Gene sequence submitted as Mox-1 (2182 base pairs), redesignated as Mox-1, submitted by A. F. Candia to New GenBank, 1992.
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