Group of synthetic antimicrobial peptides

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S334000, C514S002600

Reexamination Certificate

active

07629438

ABSTRACT:
A group of new synthetic antimicrobial peptides are disclosed, which demonstrate stronger bactericidal activity than native antimicrobial peptides. The present synthetic antimicrobial peptides can be produced by solid-phase chemical synthesis or gene expression and be used to prepare the medicines for treating the diseases induced by bacteria, viruses and fungi, as well as the anticancer drugs.

REFERENCES:
patent: 6071879 (2000-06-01), Pereira
patent: 6800727 (2004-10-01), Hahm et al.
patent: WO 95/03325 (1995-02-01), None
patent: WO 00/09553 (2000-02-01), None
patent: WO 00/09553 (2000-02-01), None
Broth, W.B. et al., Effects of Synthetic Cecropin Analogs on in Vitro Growth ofAcholeplasma laidlawii. Antimicrobial Agents and Chemotherapy 45(6): 1894-1895, 2001.
International Search Report from PCT/CNO3/00522, mailed Nov. 13, 2003.
Nakajima, Y. et al., Interaction between Liposomes and Sarcotoxin IA, a Potent Antibacterial Protein ofSarcophaga peregrina(Flesh Fly). The Journal of Biological Chemsitry 262(4): 1665-1669, 1987.
Zasloff, M. Antimicrobial peptides of multicellular organisms. Nature 415: 389-395, 2002.
Borth, Wayne B. et al., “Effects of synthetic cecropin analogs on in vitro growth ofAcholeplasma laidlawii,” Antimicrobial Agents and Chemotherapy, vol. 45, No. 6, pp. 1894-1895, Jun. 2001.
Deslouches, Berthony et al., “De novo generation of cationic antimicrobial peptides; influence of length and tryptopham substitution on antimicrobial activity,”Antimicrobial Agent and Chemotherapy, vol. 49, No. 1, pp. 316-322, Jan. 2005.
Hong, Sung Yu et al., “The effect of charge increase on the specificity and activity of a short antimicrobial peptide,”Peptides, 22, pp. 1669-1674, 2001.
Nakajima, Yuki et al., “Interaction between liposomes and sarcotoxin IA, a potent antibacterial protein ofSarcohaga peregrina(Flesh Fly),”The Journal of Biological Chemistry, vol. 262, No. 4, pp. 1665-1669, Feb. 5, 1987.
Scott, Monish et al., “Biological properties of structurally related alpha-Helical cationic antimicrobial peptides,”Infection and Immunity, pp, 2005-2009, Apr. 1999.
Zasloff, Michael, “Antimicrobial peptides of multicellular organisms,”Nature, vol. 415, pp. 389-395, Jan. 24, 2002.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Group of synthetic antimicrobial peptides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Group of synthetic antimicrobial peptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Group of synthetic antimicrobial peptides will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4076637

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.