Group B Streptococcus antigens and vaccines

Details Group B Streptococcus antigens and vaccines Group B Streptococcus antigens and vaccines

1982-02-02

1984-03-27

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 88, 536 11, 435101, A61K 3902, C08B 3700, C12P 1904

Patent

active

044394225

ABSTRACT:
Pure Group B Streptococcus antigen and Group B, Type III Streptococcus antigen are isolated, separated and purified from the culture medium in which the Group B, Type III Streptococcus are grown. The process involves (a) culturing the Group B, Type III Streptococcus in a nutrient medium, free of animal proteins and lipids, containing from 1 to 5% by weight glucose and from 0.04 M to 0.16 M phosphates; (b) separating the bacterial cells from the culture medium; (c) extracting and separating the Group B antigens and the Type III antigens from the culture medium supernatant by means of an anion exchanger; and, (d) purifying the resulting antigenic materials by chromatography on an agarose gel column. The antigens can be used as vaccines against infections caused by Group B or Group B, Type III Streptococcus.

REFERENCES:
patent: 4207414 (1980-06-01), Kasper
Kasper, D., et al., J. Immunol., vol. 121, pp. 1096-1105, 1978.
Baker, C., et al., J. Exp. Med., vol. 143, pp. 258-270, 1976.
Baker, C., et al., J. Clin. Invest., vol. 61, pp. 1107-1110, 1978.
Baker, C., et al., Infect. and Immun., vol. 13, pp. 189-194, 1976.
Baker, C., et al., J. Inf. Dis., vol. 136, pp. 137-152, 1977.
Baker, C., et al., New England Journal of Medicine, vol. 294, pp. 753-756, 1976.
Russell et al., J. Immunol., vol. 109, pp. 90-96, 1972.
Lancefield et al., J. Hygcamb., vol. 64, pp. 191-203, 1966.
Wittner, et al., J. Bact., vol. 89, pp. 398-402, 1965.
Curtis et al., Fed. Proc., vol. 23, p. 191, 1964.
Lancefield, J. Exp. Med., vol. 67, pp. 25-40, 1938.
Lancefield, J. Exp. Med., vol. 59, pp. 441-457, 1934.

Affiliated with

Also associated with

Rating

Group B Streptococcus antigens and vaccines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Group B Streptococcus antigens and vaccines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Group B Streptococcus antigens and vaccines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1755592