Group A streptococcal vaccines

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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C424S192100, C424S234100, C424S184100, C530S300000, C530S328000, C530S350000, C530S825000, C514S002600

Reexamination Certificate

active

07402316

ABSTRACT:
The present invention provides methods for eliciting an immune response against Group Astreptococci, comprising use of recombinant fusion polypeptides, and compositions thereof, that include a multivalent immunogenic portion of at least two immunogenic polypeptides from Group AstreptococciM proteins (which are capable of stimulating a protective immune response against Group Astreptococci), and a reiterated polypeptide from the immunogenic portion carboxy-terminal to the immunogenic portion, wherein the carboxy-terminal polypeptide is not required to stimulate an immune response against Group Astreptococci.

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