Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2006-01-31
2006-01-31
Ketter, James (Department: 1636)
Chemistry: molecular biology and microbiology
Vector, per se
C530S350000, C536S023100
Reexamination Certificate
active
06991936
ABSTRACT:
The invention provides a novel gene, gridlock, and its encoded protein. gridlock plays a role in vascular development and modeling, and a mutation in gridlock has been associated with an aortic arch disease, coarctation. Thus, gridlock nucleic acid molecules and polypeptides can be used in methods of diagnosing, treating, and preventing gridlock-related diseases and conditions, such as aortic arch diseases.
REFERENCES:
patent: WO 01/72777 (2001-10-01), None
patent: WO 02/31111 (2002-04-01), None
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Fishman Mark C.
Zhong Tao P.
Clark & Elbing LLP
The General Hospital Corporation
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