GRF analogs XI

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence

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Details

A61K 3702, A61K 3700, C07K 500, C07K 700

Patent

active

052625192

ABSTRACT:
The invention provides synthetic peptides which are extremely potent in stimulating the release of pituitary GH in animals, including humans and also resist enzymatic degradation in the body. Certain preferred peptides have the formula:

REFERENCES:
patent: 4649131 (1987-03-01), Felix et al.
patent: 4689318 (1987-08-01), Kaiser et al.
patent: 4843064 (1989-06-01), Vaughan et al.
patent: 5002931 (1991-03-01), Rinier et al.
patent: 5043322 (1991-08-01), Rinier et al.

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