Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2011-06-14
2011-06-14
Chin, Chris L (Department: 1641)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C422S082110, C435S808000, C436S164000, C436S172000, C436S524000, C436S525000, C436S527000, C436S805000
Reexamination Certificate
active
07960170
ABSTRACT:
A grating-based sensor is disclosed that has a grating structure constructed and designed for both evanescent resonance (ER) fluorescence detection and label-free detection applications. Some embodiments are disclosed which are optimized for ER detection in an air mode, in which the sample is dry. Other embodiments are optimized for ER detection in liquid mode, in which the sample is suspended in liquid medium such as water. One and two-dimensional gratings are also disclosed, including gratings characterized by unit cells with central posts, central holes, and two-level, two-dimensional gratings. A readout system for such sensors is also disclosed. One embodiment includes a first light source optimized for collecting label-free detection data, a second light source optimized for collecting ER fluorescence amplification data, and at least one detector. In one embodiment, the detector is an imaging system and includes a CCD camera for collecting both ER and label-free data. In other embodiments, the at least one detector takes the form of a spectrometer for collection of label-free data and a photomultiplier for collecting ER data. In other embodiments, a single light source such as a tunable laser or broad band light source is used.
REFERENCES:
patent: 4815843 (1989-03-01), Tiefenthaler
patent: 4952056 (1990-08-01), Tiefenthaler
patent: 5071248 (1991-12-01), Tiefenthaler
patent: 5216680 (1993-06-01), Magnusson et al.
patent: 5504337 (1996-04-01), Lakowicz et al.
patent: 5598267 (1997-01-01), Sambles et al.
patent: 5598300 (1997-01-01), Magnusson et al.
patent: 5925878 (1999-07-01), Challener
patent: 5955378 (1999-09-01), Challener
patent: 5986762 (1999-11-01), Challener
patent: 5994150 (1999-11-01), Challener
patent: 6035089 (2000-03-01), Gran et al.
patent: 6078705 (2000-06-01), Neuschäfer et al.
patent: 6100991 (2000-08-01), Challener
patent: 6159750 (2000-12-01), Edmonds
patent: 6207397 (2001-03-01), Lynch et al.
patent: 6277653 (2001-08-01), Challener
patent: 6289114 (2001-09-01), Mainguet
patent: 6320991 (2001-11-01), Challener
patent: 6395558 (2002-05-01), Duveneck et al.
patent: 6432632 (2002-08-01), Nakayama et al.
patent: 6448018 (2002-09-01), Nakayama et al.
patent: 6455861 (2002-09-01), Hoyt
patent: 6566143 (2003-05-01), Hoyt
patent: 6707561 (2004-03-01), Budach et al.
patent: 6870630 (2005-03-01), Budach et al.
patent: 7167615 (2007-01-01), Wawro et al.
patent: 7400399 (2008-07-01), Wawro et al.
patent: 2002/0110839 (2002-08-01), Bach et al.
patent: 2002/0127565 (2002-09-01), Cunningham et al.
patent: 2002/0135780 (2002-09-01), Budach et al.
patent: 2003/0017581 (2003-01-01), Li et al.
patent: 2003/0027327 (2003-02-01), Cunningham et al.
patent: 2003/0027328 (2003-02-01), Cunningham et al.
patent: 2003/0032039 (2003-02-01), Cunningham et al.
patent: 2003/0059855 (2003-03-01), Cunningham et al.
patent: 2003/0077660 (2003-04-01), Pien et al.
patent: 2004/0130787 (2004-07-01), Thome-Forster et al.
patent: 2004/0223881 (2004-11-01), Cunningham et al.
patent: 2005/0025421 (2005-02-01), Caracci et al.
patent: 2005/0053974 (2005-03-01), Lakowicz et al.
patent: 2006/0193550 (2006-08-01), Wawro et al.
patent: WO 90/08318 (1990-07-01), None
patent: WO 95/03538 (1995-02-01), None
patent: WO 97/29362 (1997-08-01), None
patent: WO98/09156 (1998-03-01), None
patent: WO2004/046724 (2004-06-01), None
Extended European Search Report in European Application No. 10161857.7 dated Jun. 16, 2010.
Cunningham et al., “A plastic colorimetric resonant optical biosensor for multiparallel detection of label-free biochemical interactions” Sensors and Actuators B, 85, pp. 219-226 (2002).
PCT International Search Report and Written Opinion mailed Feb. 1, 2007 for PCT application No. PCT/US2006/028473, filed Jul. 6, 2006.
Cunningham et al. “Colorimetric resonant reflection as a direct biochemical assay technique”, Sensors and Actuators B, 81: pp. 316-328 (2002).
Haes et al., “A Nanoscale Optical Biosensor: Sensitivity and Selectivity of an Approach Based on the Localized Surface Plasmon Resonance Spectroscopy of Triangular Silver Nanoparticles”, Journal of the American Chemical Society, vol. 124 No. 35 pp. 10596-10604 (2002).
Li et al., “A new method for label-free imaging of biomolecular interactions”, Sensors and Actuators B,2003.
Cantor et al., “Techniques for the Study of Biological Structure and Function”, Biophysical Chemistry Part II, p. 443 (1980).
Magnusson and Lu,Fiber Endface Bioprobes with High Sensitivity and Spatial Resolution, Grant Proposal, Aug. 11, 1999.
Tibuleac,Guided-Mode Resonance Reflection and Transmission Filters in the Optical and Microwave Spectral Ranges, Presentation, Jul. 15, 1999.
Wawro,Design, Fabrication, and Testing of Waveguide-Grating for Spectral Filters, Photonic Antennas and Optical Fiber Sensors, Presentation, Jul. 14, 1999.
Wawro and Tibuleac,Novel Diffractive Structures Integrating Waveguide Grating on Optical Fiber Endfaces, Presentation, Mar. 24, 1999.
Shin, et al,Thin-Film Optical Filters with Diffractive Elements and Waveguides, Opt. Eng., Sep. 1998.
Brundrett, et al.,Normal-Incidence Guided-Mode Resonant Grating Filters: Design and Experimental Demonstration, Optical Letters, May 1, 1998.
Norton,Resonant Grating Structures: Theory, Design, and Applications, Doctoral Thesis—The University of Rochester, 1997.
Tibuleac and Magnusson,Reflection and Transmission Guided-Mode Resonance Filters, J. Opt. Soc. Am.A., Jul. 1997.
Tibuleac and Magnusson,Diffractive Narrow-Band Transmission Filters Based on Guided-Mode Resonance Effects in Thin-Film Multilayers, IEEE Photonics Technology Letters, Apr. 1997.
Peng,Polarization-control Components and Narrow-band Filters Based on Subwavelength Grating Structures, Doctoral Thesis—The University of Rochester, 1996.
Peng and Morris,Experimental Demonstration of Resonant Anomalies in Diffraction from Two-Dimensional Grating, Optics Letters, 1996.
Magnusson and Wang,Transmission Bandpass Guided-Mode Resonance Filters, Applied Optics, 1995.
Wang and Magnusson,Design of Waveguide-Grating Filters with Symmetrical Line Shapes and Low Sidebands, Optical Letters, 1994.
Wang and Magnusson,Theory and Applications of Guided-Mode Resonance Filters, Applied Optics, 1993.
Wang, et al.,Guided-Mode Resonance in Planer Dielectric-layer Diffraction Grating, J. Opt. Soc. Am. A., 1990.
Nellen et al.,Integrated Optical Input Grating Couplers as Biochemical Sensors, Sensors and Actuators, 1988.
Lukusz and Tiefenthaler,Sensitivity of Integrated Optical Grating and Prism Couplers as(Bio)chemical Sensors, Sensors and Actuators, 1988.
Popov, et al.,Theoretical Study of the Anomalies of Coated Dielectric Gratings, Optica Acta, May 1986.
Tiefenthaler and Lukusz,Integrated Optical Switches and Gas Sensors, Optics Letters, Apr. 1984.
International Preliminary Report on Patentability dated Jul. 6, 2007 in PCT/US2006/028473 filed Jul. 20, 2006.
Office Action in European Patent Application No. 06 824 773.3 dated May 23, 2008.
Wawro et al.,Optical Fiber Endface Biosensor Based on Resonances in Dielectric Waveguide Gratings, International Biomedical Optics Symposium Jan. 2000, Proceedings SPIE, vol. 3911, pp. 86-94 (2000).
Binder Brant
Borsody Alex
Cunningham Brian T.
Jogikalmath Gangadhar
Laing Lance G.
Chin Chris L
McDonnell Boehnen Hulbert & Bershoff LLP
SRU Biosystems Inc.
LandOfFree
Grating-based sensor combining label-free binding detection... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Grating-based sensor combining label-free binding detection..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Grating-based sensor combining label-free binding detection... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2681304