Graphitic nanotubes in luminescence assays

Details Graphitic nanotubes in luminescence assays Graphitic nanotubes in luminescence assays

1996-03-06

1999-02-02

Ceperley, Mary E.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

435 6, 435 74, 435 75, 435 792, 435 793, 435 794, 435 24, 435 26, 435176, 435182, 436524, 436535, 436806, 5303911, 5303913, 5303915, G01N 33551, G01N 33573, C12Q 132, C12Q 137

Patent

active

058664343

ABSTRACT:
Graphitic nanotubes, which include tubular fullerenes (commonly called "buckytubes") and fibrils, which are functionalized by chemical substitution, are used as solid supports in electrogenerated chemiluminescence assays. The graphitic nanotubes are chemically modified with functional group biomolecules prior to use in an assay. Association of electrochemiluminescent ruthenium complexes with the functional group biomolecule-modified nanotubes permits detection of molecules including nucleic acids, antigens, enzymes, and enzyme substrates by multiple formats.

REFERENCES:
patent: 5310669 (1994-05-01), Richmond et al.
patent: 5547748 (1996-08-01), Ruoff et al.
patent: 5554751 (1996-09-01), Kampe
patent: 5582955 (1996-12-01), Keana et al.

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