Granules having core and their production

Details Granules having core and their production Granules having core and their production

1994-08-09

1999-01-05

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424461, 424480, 514781, A61K 916, A61K 936, A61K 962

Patent

active

058559140

ABSTRACT:
Granules having a core are produced by spraying core granules with a dispersion of a low substituted hydroxypropylcellulose (L-HPC), and, if necessary, simultaneously applying a dusting powder. The granules having a core thus obtained exhibit increased granule strength and improved disintegrating property as compared with those produced by known methods. An active ingredient such as a drug can be contained in the dispersion, dusting powder or core granules.

REFERENCES:
patent: 3664963 (1972-05-01), Pasin
patent: 4261971 (1981-04-01), Appelgren et al.
patent: 4568559 (1986-02-01), Nuwayser et al.
patent: 4606909 (1986-08-01), Bechgaard et al.
patent: 4704285 (1987-11-01), Alderman
patent: 4871549 (1989-10-01), Ueda et al.
patent: 4975275 (1990-12-01), Kehoe
patent: 5026560 (1991-06-01), Makino et al.

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