Granulation process

Details Granulation process Granulation process

1977-05-09

1978-09-05

Custer, Jr., Granville Y.

Solid material comminution or disintegration

Processes

With application of fluid or lubricant material

241 24, B02C 2330

Patent

active

041113713

ABSTRACT:
This invention provides a process for the preparation of dry-medicament granulation. An apparatus for practicing such process comprises an enclosed-circular mixing chamber containing mixing means with a separate air inlet means and air outlet means, both of which are in flow communication with the chamber. The air outlet means is provided with a collecting means for collecting the dry-fine particles of the medicament granulation and may be equipped with a vibrator or other means for returning them to the mixing chamber. The process provides a one step preparation in a batch process of medicament granulations, whereby the granulation may be directly compressed into solid-dosage forms without further processing.

REFERENCES:
patent: 3713594 (1973-01-01), Blakely et al.
patent: 3877649 (1975-04-01), Herfeld

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