Granulating composition and method

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

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424461, 424462, 424439, 424441, 424465, 424466, 424493, 424494, 424495, 424497, 424498, 424601, 424606, 514692, 514715, 514722, A61K 926, A61K 946

Patent

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049650726

ABSTRACT:
The invention involves a granulating composition composed of an aqueous solution of magnesium sulfate heptahydrate and sodium hexametaphosphate. This composition can be used to prepare granules of ingredients for inclusion in any formulation for which rapid disintegration or dispersion are important factors. It is useful for tablets containing ingredients which are difficult to compress and is particularly useful for formulating swallowable tablets of a single non-soluble ingredient such as calcium carbonate. Disintegration times are markedly decreased.

REFERENCES:
patent: 4201756 (1980-05-01), Saeman et al.
patent: 4439453 (1984-03-01), Vogel
patent: 4582709 (1986-04-01), Peters et al.

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