Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1995-09-13
1997-06-24
Phelan, D. Gabrielle
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424 43, 424 44, 424490, 424493, 424494, 424496, 424686, 424700, 514777, 514781, 514782, A61K 948
Patent
active
056415117
ABSTRACT:
A novel granular drug delivery system having a gel-forming dietary fiber that can be made into a an orally-ingestible dispersion by admixture with a liquid that can deliver an effective dose of a pharmaceutically-active compound. The granular drug delivery system comprises granules consisting essentially of a pharmaceutically active compound, and a gel-forming dietary fiber, the granules being coated with at least one of the following: a gel-forming dietary fiber, a starch or a protein. The composition may further include a mineral salt that releases a physiologically-acceptable gas upon ingestion. The composition of the granular drug delivery system will deliver microgram quantities of a pharmaceutically-active compound in an orally-ingestible dispersion without forming a thick gel and without forming "hot" and "cold" spots of the pharmaceutically-active compound.
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Cibus Pharmaceutical
Phelan D. Gabrielle
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