Gram positive bacteria deprived of HtrA protease activity...

Details Gram positive bacteria deprived of HtrA protease activity... Gram positive bacteria deprived of HtrA protease activity...

2006-02-07

2006-02-07

Graser, Jennifer E. (Department: 1645)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using a micro-organism to make a protein or polypeptide

C435S069100, C435S243000, C435S252300, C435S252900, C435S253400, C424S234100, C424S200100, C424S244100, C424S246100

Reexamination Certificate

active

06994997

ABSTRACT:
The invention concerns bacteria strains, obtained from gram-positive bacteria whereof the genome size is not more than 3.2 Mb, and wherein the HtrA surface protease is inactive. Said strains are useful for expressing exported proteins of interest.

REFERENCES:
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Bayles et al. Abstracts of the 97th Gen.Meeting of the ASM. May 4-8, 1997, p. 363. K-129.
Smeds et al., 1998, Journal of Bacteriology, v. 180, No. 23, p. 6148-6153.
Pallen et al., 1997, Molecular Microbiology, 26(2), p. 209-221.

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