Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Digestive system
Patent
1993-12-15
1994-12-13
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Digestive system
623 1, 623 11, 623 12, 623 13, 623 14, 623 16, 623 18, 623 19, 623 20, 623 21, A61K 3538
Patent
active
053728211
ABSTRACT:
Surgical repair of diseased or damaged endogenous connective tissue can be accomplished using a tissue graft formed from a delaminated segment of intestinal tissue. The tissue graft comprises the intestinal tunica submucosa and basilar mucosa tissue delaminated from the tunica muscularis and the luminal portion of the tunica mucosa. The graft can be conditioned by stretching and formed as a multilayer composition for high tensile strength and resistance to tearing at its points of attachment to existing physiological structures.
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"Replacement of Dog's Aorta by Autologous Intestinal Muscle in the Infected Retroperitoneum", R. Broll, et al., Eurp. Surg. Res., 18: 390-396 (1986).
"Aortic Replacement with Multi-Layer Submucosa Prostheses Made From Heterologous Small Intestine", G. Rotthoff, et al., presented at 8th Congress of the International Society of Cardiovascular Surgery, Vienna, Sep. 7-9, 1967.
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"Replacement of the Abdominal Aorta With A Small-Intestine Muscle Tube In An Animal Experiment", J. Huth, Zentralbl Chir., 92 (26/2): 1817-19 (1967).
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"Replacement of the Aorta by Multilayered Submucosa Prostheses of Heterologous Ileum", G. Rotthoff, et al., Bulletin de la Societe International de Chirurgie, No. 2, 1969, 256-259.
Badylak Stephen F.
Coffey Arthur C.
Geddes Leslie A.
Lantz Gary C.
Shelbourne K. Donald
Purdue Research Foundation
Robinson Douglas W.
Witz Jean C.
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