Graft copolymers and graft copolymer/protein compositions

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...

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525 69, 525 87, 525193, 525204, 525240, 525241, 525242, 525243, 525244, 525260, 525263, 525265, 5253279, 5253333, 525375, 525435, 525525, 525530, G01N 3353, C12Q 100

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054667470

ABSTRACT:
Graft copolymers comprising a poly-alpha-olefin base polymer selected from the group consisting of polyethylene, polypropylene, polystyrene, and compatible mixtures thereof, having grafted thereto an olefinic monomer. The grafted monomer is present in an amount effective to increase the amount of protein that will bind to the graft copolymer as compared with the base polymer. Also disclosed are polymer/protein compositions comprising a graft copolymer having a protein immobilized on the surface thereof, processes for the preparation of the above-described graft copolymers and compositions, methods of immobilizing proteins, and methods of immunoassay based on such immobilization.

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