Graft co-polymer adducts of platinum (II) compounds

Details Graft co-polymer adducts of platinum (II) compounds Graft co-polymer adducts of platinum (II) compounds

1996-10-28

1999-02-16

Kight, John

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

424 169, 424 934, 424 935, 424 936, 424 9364, 424 7817, 514 6, 514 54, A61K 5108, A61K 4900, A61K 3174, A61K 3714

Patent

active

058717102

ABSTRACT:
A biocompatible graft co-polymer adduct including a polymeric carrier, a protective chain linked to the polymeric carrier, a reporter group linked to the carrier or to the carrier and the protective chain, and a reversibly linked Pt(II) compound. The invention also relates to a method of treating a disease in a patient, particularly cancer, by administering to the patient a therapeutically effective amount of the adduct, and may include scanning the patient using an imaging technique which can provide a visible image of the distribution of the adduct.

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