Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone
Patent
1995-01-03
1996-02-06
Isabella, David
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
Bone
623 20, 623 23, A61F 228, A61F 232
Patent
active
054893062
ABSTRACT:
A surgical prosthetic implant comprises a metallic substrate for insertion into the cavity of a long bone. A porous coating is provided on the substrate for encouraging bone and tissue ingrowth. The porous coating comprises at least a layer of particles of metallic material, which may be of the same material as the substrate. Graduated sized particles are used from proximal to distal ends of the implant creating graduated pore size between particles from proximal to distal ends. At a first zone at a proximal end of the substrate, the particles have a pore size in the range of approximately 325-425 microns for optimal bone-to-implant load transfer. At a second zone, advancing toward a distal end of the substrate, the particles have a pore size in the range of approximately 250-325 microns for significant bone ingrowth in a shorter time interval. At a third zone, the particles have a pore size in the range of approximately 175-250 microns for some bone ingrowth and some soft tissue ingrowth. At a fourth zone, the particles have a pore size in the range of approximately 100-175 microns for optimal soft tissue ingrowth with minimal bone ingrowth. At a fifth zone, the particles have a pore size of less than approximately 100 microns for optimal soft tissue ingrowth without permitting bone ingrowth. The porous coating may be of the same material as the substrate, which may be of stainless steel, titanium, titanium alloys, or chromium-cobalt alloys.
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