Liquid purification or separation – With means to add treating material – Chromatography
Patent
1990-06-11
1992-10-27
Therkorn, Ernest G.
Liquid purification or separation
With means to add treating material
Chromatography
210101, 210143, 137 88, 417503, B01D 1508
Patent
active
051586754
ABSTRACT:
To supply a programmed gradient to a high pressure pump for introduction into a column, a mixer, degasser and accumulator communicates with the high pressure pump to supply fluid thereto, having a volume no more than 150 times the chamber volume of the high pressure pump. The mixer, degasser and accumulator includes temperature sensors which sense when the mixer, degasser and accumulator has been emptied to a level where it cannot respond to a demand for fluid from said high pressure pump and provides a signal to a low pressure pump which responds by cycling to again fill the mixer, degasser and accumulator. Upon receiving a demand signal, the low pressure pump fills by drawing fluid from a plurality of fluid sources to compose the gradient being used at that time, with the pump slowing during valve opening and closing so as to avoid cavitation.
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"Monitoring Solenoid Valve Position" by Lewis Research Center, Instrumentation Technologies, vol. 17, No. 6, Jun. 1970, p. 67.
Keatos, Spectroflow 430, Publication #251-42221 (1984) pp. 1 and 2.
Allington Robert W.
Jameson Daniel G.
Carney Vincent L.
Isco, Inc.
Therkorn Ernest G.
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