Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ketone doai
Reexamination Certificate
2005-01-06
2010-12-14
Fetterolf, Brandon J (Department: 1628)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ketone doai
C514S569000, C514S681000, C514S700000, C514S548000, C568S327000, C568S043000
Reexamination Certificate
active
07851510
ABSTRACT:
The present invention relates to compounds of general formula (1):in which, independently of each other, R1and R2represent:—OH, or—CH2—O—R3, or—CH2—S—R3, orR3, R4, R5and R6representing, independently of each other, —H or a carbon-containing group with1to10carbon atoms, saturated or unsaturated, optionally substituted with one or more heteroatomic groups.The invention also relates to pharmaceutical compositions containing these compounds, and their uses, in particular in the context of the treatment of cancer.
REFERENCES:
patent: 5385936 (1995-01-01), Reidenberg et al.
patent: 01/00554 (2001-01-01), None
Dao et al. New thioderivatives of gossypol and gossypolone, as prodrugs of cytotoxic agents. Bioorganic & Medicinal Chemistry, 11, 2003, 2001-2006.
Haas et al. The oxidation of Gossypol. II. Formation of gossypolone with ferric chloride. J. Org. Chem. 30(12), pp. 4111-4113. 1965.
V-T. Dao et al: “New thioderivatives of gossypol and gossypolone, as prodrugs of cytotoxic agents” Biooraganic and Medicinal Chemistry, vol. 11, 2003, pp. 2001-2006.
Dao V-T et al: “Synthesis and cytotoxicity of gossypol related compunds” Euorpean Journal of Medicinal Chemistry Editions Scientifique Elsvier, Paris, FR, vol. 35, No. 9, Sep. 2000, pp. 805-8013.
Dao Vi-Thuy
De Gunzburg Jean
De Mil Oliver Christophe
Michelot Robert
Centre National de la Recherche Scientifique (C.N.R.S.)
Fetterolf Brandon J
Institut National de la Sante et de la Recherche Medicale (I.N.S
Pagonakis Anna
Young & Thompson
LandOfFree
Gossypol derivatives, production method thereof and uses of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Gossypol derivatives, production method thereof and uses of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gossypol derivatives, production method thereof and uses of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4185870