Gossypol acetic acid for the treatment of cancer

Details Gossypol acetic acid for the treatment of cancer Gossypol acetic acid for the treatment of cancer

1990-07-12

1995-01-31

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514569, A61K 31225, A61K 3119

Patent

active

053859367

ABSTRACT:
A method for treating cancer in a human, which comprises administering to the human subject an anti-cancer effective amount gossypol acetic acid. Also included is a method for treating cancer in a human which comprises administering to the human subject an anti-cancer effective amount of gossypol acetic acid in combination with an anti-cancer effective amount of other conventional chemotherapeutic agents. Finally, the invention also encompasses a pharmaceutical composition comprising an anti-cancer effective amount of gossypol acetic acid, and an anti-cancer effective amount of a conventional chemotherapeutic agent, or combinations of the latter.

REFERENCES:
Kim et al., 1984, Contraception 312:5966-72.
Qian et al., 1984, Annual Review of Pharmcological Toxicology, vol. 24:329-60.
Rao et al., 1985, Cancer Chemother. Pharmacol., vol. 15, pp. 2-25.
Tanphaichitr et al., Biology of Reproduction, vol. 31, pp. 1049-1060, 1984.
Tso, Cancer Letters, vol. 24, pp. 257-261, 1984.
Wu et al., Cancer Research, vol. 49, pp. 3754-3758, Jul. 15, 1989.

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