Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1984-03-19
1987-09-29
Kepplinger, Esther M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
424 92, 435820, 435871, 436528, 530352, 530825, G01N 33531, G01N 33544, G01N 33569, A61K 39095
Patent
active
046968962
ABSTRACT:
There are provided a crystalline and single rod products derivable from the Pili of Type 1 and Type 2 Neisseria gonorrhoese organisms. There are provided methods of growing said organisms to produce the maximum yield of Pili and procedures for purifying said Pili to produce said crystalline material. There are further provided methods of utilizing said Pili to determine the presence, in a system infectable by N. gonorrhoese organisms, of antibodies to the Pili of said organisms, and methods of serotyping said Pili. There is also provided a mode of utilizing said crystalline material to provide a substantial degree of immunization infection by N. gonorrhoese in mammalian systems susceptible to such infection.
REFERENCES:
patent: 4461838 (1924-07-01), Brinton et al.
J. B. G. Kwapinski Methodology of Immunochemical and Immunological Research, Wiley-Interscience, New York, 1972, pp. 296-304.
Buchanan et al., J. Clin Invest 52 (1973) 2896-2909.
Brinton Charles C.
McMichael John C.
Bactex, Inc.
Behr Omri M.
Kepplinger Esther M.
Saunders David A.
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