Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-09-11
2008-12-09
Balasubram, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S272000, C514S275000, C544S309000, C544S310000, C544S311000, C544S314000
Reexamination Certificate
active
07462625
ABSTRACT:
GnRH receptor antagonists are disclosed that have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure:wherein A, Q, R1, R2, R3a, R3b, R4, R5, R6and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
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Chen Chen
Gross Timothy D.
Guo Zhiqiang
Rowbottom Martin
Struthers R. Scott
Balasubram Venkataraman
Neurocrine Biosciences Inc.
Seed IP Law Group PLLC
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