Gona-4,9(10)-dienes and process of producing the same

Details Gona-4,9(10)-dienes and process of producing the same Gona-4,9(10)-dienes and process of producing the same

1977-07-18

1979-09-11

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26023955R, 2603975, 260349, C07J 100

Patent

active

041675177

ABSTRACT:
New gona-4,9(10)-dienes of formula I ##STR1## where R is alkyl of 1 to 3 carbon atoms and X is Cl, Br, F, N.sub.3, SCN, CN, OH, OR'(R'=alkyl), NH.sub.2, a substituted amino group or a heterocyclic compound including nitrogen in the ring. The compounds have valuable biological properties, especially hormonal and antihormonal effects, and can be used to advantage in pharmaceutical preparations for the treatment of endocrinopathies and for reproduction control in human beings and livestock.
The invention also embraces a process for making the compounds by converting 3-methyoxy-13.beta.-R-gona-2,5(10)-diene-17.beta.-spiro-1',2'-o xiranes first to 17.beta.-hydroxy-17.alpha.-CH.sub.2 X-13.beta.-R-gon-5(10)-en-3-one, then to the 17.beta.-hydroxy-17.alpha.-CH.sub.2 X-13.beta.-R-gona-4,9(10)-diene-3-ones of formula I.

REFERENCES:
patent: 3484464 (1969-12-01), Farkas
patent: 3506652 (1970-04-01), Creger
Journal Chem. Soc., (1964), pp. 4479-4492, by Smith et al.

Affiliated with

Also associated with

Rating

Gona-4,9(10)-dienes and process of producing the same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gona-4,9(10)-dienes and process of producing the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gona-4,9(10)-dienes and process of producing the same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-477719