Gold sol immunoassay system and device

Details Gold sol immunoassay system and device Gold sol immunoassay system and device

1992-01-09

1994-08-02

Scheiner, Toni R.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

422 55, 422 56, 422 57, 422 58, 422101, 422102, 436164, 436165, 436169, 436518, 436805, 436807, 436810, G01N 33553

Patent

active

053345380

ABSTRACT:
A new apparatus and method for immunoassays. A gold sol bead is held in a funnel member. First antibodies are associated with the gold sol bead. When the sample contacts the gold sol it dissolves the bead. A second antibody is impregnated on an immunosorbent surface. When the dissolved gold sol passes this surface, any antigen already reacted with the first antibody present reacts with the second antibody forming a gold: first antibody: antigen: second antibody: immunosorbent complex. The gold sol acts as the visible label.

REFERENCES:
patent: 4313734 (1982-02-01), Leuvering
patent: 4780285 (1988-10-01), Kuypers et al.
patent: 4912034 (1990-03-01), Kalra et al.
patent: 4965187 (1990-10-01), Tonelli
patent: 4999163 (1991-03-01), Lennon et al.
patent: 5006464 (1991-04-01), Chu et al.

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