GnRH Antagonists

Details GnRH Antagonists GnRH Antagonists

1983-11-29

1985-10-15

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

2601125LH, C07C10352, A61K 3702

Patent

active

045473706

ABSTRACT:
Peptides which inhibit the secretion of gonadotropins by the pituitary gland and inhibit the release of steroids by the gonads. Administration of an effective amount prevents ovulation of female mammalian eggs and/or the release of steroids by the gonads. The peptides have the structure:

REFERENCES:
patent: 4234571 (1980-11-01), Nestor et al.
patent: 4253997 (1980-03-01), Sarantakis
patent: 4317815 (1980-06-01), Coy et al.
patent: 4341767 (1980-10-01), Nestor et al.
patent: 4444759 (1984-04-01), Rivier et al.
Coy et al., Endocrinology, 110, No. 4, 1445-1447 (1982).

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