Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Reexamination Certificate
2006-08-16
2010-02-23
Raghu, Ganapathirama (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
C435S419000, C435S468000, C536S023200, C800S300000
Reexamination Certificate
active
07666643
ABSTRACT:
Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
REFERENCES:
patent: 4535060 (1985-08-01), Comai
patent: 4769061 (1988-09-01), Comai
patent: 4940835 (1990-07-01), Shah et al.
patent: 4971908 (1990-11-01), Kishore et al.
patent: 5145783 (1992-09-01), Kishore et al.
patent: 5188642 (1993-02-01), Shah et al.
patent: 5310667 (1994-05-01), Eichholtz et al.
patent: 5312910 (1994-05-01), Kishore et al.
patent: 5463175 (1995-10-01), Barry et al.
patent: 5491288 (1996-02-01), Chaubet et al.
patent: 5510471 (1996-04-01), Lebrun et al.
patent: 5605011 (1997-02-01), Bedbrook et al.
patent: 5627061 (1997-05-01), Barry et al.
patent: 5633435 (1997-05-01), Barry et al.
patent: 5633448 (1997-05-01), Lebrun et al.
patent: 5776760 (1998-07-01), Barry et al.
patent: 5804425 (1998-09-01), Barry et al.
patent: 5866775 (1999-02-01), Eichholtz et al.
patent: 6130366 (2000-10-01), Herrera-Estrella et al.
patent: 6225114 (2001-05-01), Eichholtz et al.
patent: 6248876 (2001-06-01), Barry et al.
patent: 6448476 (2002-09-01), Barry
patent: 6500617 (2002-12-01), Stemmer et al.
patent: 6605430 (2003-08-01), Affholter et al.
patent: 7018794 (2006-03-01), Berka et al.
patent: 2002/0146721 (2002-10-01), Berka et al.
patent: 2003/0083480 (2003-05-01), Castle et al.
patent: 2004/0082770 (2004-04-01), Castle et al.
patent: 2005/0246798 (2005-11-01), Castle et al.
patent: 2006/0191033 (2006-08-01), Castle et al.
patent: 2006/0200874 (2006-09-01), Castle et al.
patent: 2007/0004912 (2007-01-01), Castle et al.
patent: 0218571 (1987-04-01), None
patent: WO 97/04103 (1997-02-01), None
patent: WO 97/04103 (1997-02-01), None
patent: WO 98/39419 (1998-09-01), None
patent: WO 98/44140 (1998-10-01), None
patent: WO 00/09727 (2000-02-01), None
patent: WO 00/09727 (2000-02-01), None
patent: WO 00/29596 (2000-05-01), None
patent: WO 00/66746 (2000-11-01), None
patent: WO 00/66747 (2000-11-01), None
patent: WO 01/66704 (2001-09-01), None
patent: WO 01/66704 (2001-09-01), None
patent: WO 02/29113 (2002-04-01), None
patent: WO 02/36782 (2002-05-01), None
patent: WO 2003/092360 (2003-11-01), None
patent: WO 2003/092360 (2003-11-01), None
Whisstock et al., Prediction of protein function from protein sequence. Q. Rev. Biophysics., 2003, vol. 36 (3):307;340.
M. Leonardo Satz and Alberto R. Kornblihtt, “The Polymerase Chain Reaction”,Ciencia Hoy, vol. 4, No. 23, Mar./Apr. 1993 (Argentina).
U.S. Appl. No. 60/096,288, filed Aug. 12, 1998, Maxygen, Inc.
Kunst, F., et al., “The Complete Genome Sequence of the Gram-positive BacteriumBacillus subtilis,” Nature, 1997, pp. 249-256, vol. 390.
Kunst, F., et al., “Hyperbolized Protein BS611000 (Bacillus subtilissubsp. Str. 168),” 1997, GenBank Accession No. NP-388981.
Rey, M.S., et al “Complete Genome Sequence of the Industrial BacteriumBacillus licheniformisand Comparisons with Closely RelatedBacillusSpecies,”Genome Biology, Sep. 13, 2004, R77, vol. 5.
Roche et al., “ABacillus subtilisChromosome Segment of the 100 Degree to 102 Degree Position Encoding 11 Membrane Proteins,”Microbiology, 1997, pp. 3309-3312, vol. 143.
Whittstock, J.C. and A.M. Lesk, “Prediction of Protein Function from Protein Sequence and Structure,”Q. Rev. Biophys, Aug. 2003, pp. 307-340, vol. 36, No. 3.
ExPASy Sequence Alignment for SEQ ID No. 445-584, Apr. 18, 2005.
Castle, L.A., et a., “Discovery and Direct Evolution of a Glyphosate tolerance Gene,”Science, May 21, 2004, pp. 1151-1154, vol. 304.
Padgette et al., “New Weed Control Opportunities: Development of Soybeans with a Round Up Ready™”,Herbicide-Resistant Crops, 1996, pp. 54-84.
Aono, M., et al., “Paraquat Tolerance of Transgenic nicotiana Tabacum with Enhanced Activities of Glutahione Reductase and Superoxide Dismutase,”,Plant Cell Physiol, 1995, p. 1687, vol. 36.
Datta, S., et al., “Herbicide-resistant Indica Rice Plants from IRRI Breeding Line IR72 After PEG-medicated Transformation of Protoplasts,”Plant Mol Biol, 1992, p. 619, vol. 20.
Hattori, J., et al., “An Acetohydroxy Acid Synthase Mutant Reveals a Single Site Involved in Multiple Herbicide Resistance,”Mol Gen Genet, 1995, p. 419, vol. 246.
Kunst et al., Unst et al., “YITI Protein,”, EMBL Database Accession No. 006744, Jul. 1, 1997 [Abstract].
Shiota, N., et al., “Herbicide-Resistant Tobacco Plants Expressing the Fused Enzyme Between Rat Cytochrome P4501A1 (CYP1A1) and yeast NADPH-Cytochrome P450 Oxidoreductase,”Plant Physiol, 1994, p. 17, vol. 106.
Vasil, “Phosphinothricin-Resistant Crops,” inHerbicide-Resistant Crops(Duke, et), 1996, pp. 85-91, CRC Press, boca Raton, FL.
Broun, P., et al., “Catalytic Plasticity of Fatty Acid Modification Enzymes Underlying Chemical Diversity of Plant Lipids”, Nov. 1998,Science, vol. 282, pp. 1315-1317.
Guo, H.H. and Loeb, L.A., “Protein Tolerance to Random Amino Acid Change”, Jun. 2004,PNAS, vol. 101, No. 25, pp. 9205-9210.
Seffernick, J.L., et al., “Melamine Deaminase and Atrazine Chlorohydrolase: 98 Percent Identical but Functionally Different”, Apr. 2001,Journal of Bacteriology, vol. 183, No. 8, pp. 2405-2410.
Witkowski, A., et al. “Conversion ofβ-Ketoacyl Synthase to a Malonyl Decarboxylase by Replacement of the Active-Site Cysteine with Glutamine”, 1999,Biochemistry, vol. 38, pp. 11643-11650.
NCBI Report for Accession No. CAA70664, Direct Submission Nov. 14, 1996.
Eddy, Sean R., “Where did the BLOSUM62 Alignment Score Matrix Come From?”Nature Biotechnology, vol. 22, No. 8, Aug. 2004, pp. 1035-1036.
Kisselev, L., “Polypeptide Release Factors in Prokaryotes and Eukaryotes: Same Function, Different Structure,”Structure, 2002, pp. 8-9, vol. 10, Elsevier Ltd.
Castle Linda A.
Chen Yong Hong
Duck Nicholas B.
Giver Lorraine
Ivy Cristina
Alston & Bird LLP
Pioneer Hi-Bred international, Inc.
Raghu Ganapathirama
Verdia Inc.
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