Glyoxylic acid/aminomethylphosphonic acid mixtures prepared usin

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435190, 435192, 4351721, C12P 740, C12P 1300, C12N 904

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active

055410944

ABSTRACT:
An improved enzymatic process for reacting glycolic acid and oxygen in an aqueous solution in the presence of aminomethylphosphonic acid wherein the improvement comprises using a microbial cell catalyst that expresses glycolate oxidase (e.g., Pichia pastoris, Hansenula polymorpha, Aspergillus nidulans, or Escherichia coli) and endogenous catalase; soluble catalase may also be included. The resulting mixtures are useful intermediates in the production of N-(phosphonomethyl)glycine.

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