Glycylglycine amide preparations and method of use antiarrhythmi

Details Glycylglycine amide preparations and method of use antiarrhythmi Glycylglycine amide preparations and method of use antiarrhythmi

1975-06-13

1976-08-24

Gotts, Lewis

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

A61K 3700

Patent

active

039767710

ABSTRACT:
A novel class of glycylglycine amides has been discovered having value as antiarrhythmic agents. The preferred compound of the present invention has the structural formula ##EQU1## Also included within the scope of this invention are compounds having C.sub.1 -C.sub.3 alkyl, alkoxy and halo substituents in the ortho, para or meta positions of the aromatic ring, compounds in which the phenyl group is replaced by benzyl or substituted benzyl and compounds in which the glycylglycine chain may be substituted with lower alkyl groups or may contain heterocyclic rings.

REFERENCES:
koelzer et al.: Arzneimittelforschung, 9 (1952), pp. 167-175.
Pfeiffer et al.: Journal Fur Praktische Chemie, vol. 157, pp. 123-124 (1941).

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