Glycosylation-deficient hepatocyte growth factor

Details Glycosylation-deficient hepatocyte growth factor Glycosylation-deficient hepatocyte growth factor

2004-12-15

2010-06-22

Allen, Marianne P (Department: 1647)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Hormones, e.g., prolactin, thymosin, growth factors, etc.

Reexamination Certificate

active

07741452

ABSTRACT:
The invention provides a modified glycosylation-deficient HGF and a production method thereof. The glycosylation-deficient HGF is produced by introducing amino acid mutation(s) so that no glycosylation take place at at least one glycosylation site of hepatocyte growth factor.

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