Glycosylated steroid derivatives for transport across biological

Details Glycosylated steroid derivatives for transport across biological Glycosylated steroid derivatives for transport across biological

1994-06-23

1997-05-06

Kight, John

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 536 241, 536 243, 514 26, 514 44, C07J 1700, C07H 2102, C07H 2104

Patent

active

056272707

ABSTRACT:
Novel glycosylated steroid derivatives for facilitating the transport of compounds across biological membranes, either in admixture or as conjugates, are disclosed. A novel process for efficient synthesis of these glycosylated steroid derivatives, using activated glycosyl sulfoxide intermediates is provided. Methods for the permeabilization of membranes and the enhancement of the activity of predetermined compounds are also provided.

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