Glycosylated hemoglobin measurement

Chemistry: physical processes – Physical processes – Crystallization

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Details

23230B, 23901, 23913, 252408, 422 58, 422 59, 422 61, 422 68, 424 1, G01N 3352, G01N 3366, G01N 3372, G01N 3358

Patent

active

042682703

ABSTRACT:
Process and apparatus for measuring glycosylated hemoglobin by assaying bound glyco groups in hemolysate featuring, in one aspect, appropriate oxidation of glycosylated hemoglobin and the rapid measurement of the resultant aldehydic compounds.

REFERENCES:
patent: 4142855 (1979-03-01), Acuff
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L. A. Trivelli et al., N. Eng. J. Med., 284, pp. 353-357 (1971).
H. Franklin Bunn et al., J. Clin. Invest., 57, pp. 1652-1659 (Jun. 1976).
R. Fluckiger et al., FEBS Letters, 71(2), pp. 356-360 (Dec. 1976).
H. Franklin Bunn et al., Biochem and Biophys, Research Communications, 67(1), pp. 103-109 (1975).
H. Franklin Bunn et al., Science, 200, pp. 21-27 (Apr. 1978).
Chemical Abstracts, 69:49194c (1968).
H. Franklin Bunn et al., paper entitled "Structural Heterogeneity of Human Hemoglobin", Presented in Part of the American Society of Biological Chemists, Jun. 1978.
K. H. Gabbay et al., J. Clin. Endocrinology and Metabolism, 44(5), pp. 859-864 (May 1977).
Y. Massamiri et al., Anal. Biochem, 91, pp. 618-625 (1978).
K. H. Gabbay et al., paper entitled "Glycoslated Hemoglobins: Increased Glycosylation of Hemoglobin A in Diabetic Patients", Presented in Part at Annual Meeting of the American Society for Clinical Investigation, San Francisco, Calif., May 1, 1978.

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