Glycosyl sulfotransferases GST-4α, GST-4β, and...

Details Glycosyl sulfotransferases GST-4α, GST-4β, and... Glycosyl sulfotransferases GST-4α, GST-4β, and...

2005-02-08

2005-02-08

Monshipouri, Maryam (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

C435S320100, C435S325000, C435S252300, C435S006120, C536S023200

Reexamination Certificate

active

06852518

ABSTRACT:
Novel glycosylsulfotransferases (GST-4α, GST-4β, and GST-6) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including various diagnostic and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith, particularly by administering an inhibitor of at least one of GST-4α, GST-4β, and GST-6.

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