Glycosphingolipids with a group capable of coupling in the sphin

Details Glycosphingolipids with a group capable of coupling in the sphin Glycosphingolipids with a group capable of coupling in the sphin

1989-11-24

1997-02-04

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 185, 536 187, 536 53, 536 551, 536 553, 530395, C07G 300, C07G 3700, C07H 504

Patent

active

055999140

ABSTRACT:
The invention relates to the chemical modification of the sphingoid portions of glycosphingolipids. It has been possible by a series of reactions to introduce an amino group in the position of the carbon double-bond in the sphingoid portion after elimination of the long-chain aldehyde. Glycosphingolipids of the formula (2) and (3), where X and Y denote a group capable of coupling, are suitable for coupling to other molecules, preferably proteins. X preferably represents NH.sub.2, and Y preferably represents ##STR1##

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