Glycosaminoglycan-modified protein

Details Glycosaminoglycan-modified protein Glycosaminoglycan-modified protein

1992-07-02

1994-05-10

Wityshyn, Michael G.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Glycoprotein, e.g., mucins, proteoglycans, etc.

C07K 1514

Patent

active

053108817

ABSTRACT:
A glycosaminoglycan-modified protein wherein an amino group of a protein is bound to an aldehyde group, which has been formed by reducing and partially oxidizing the reducing terminal sugar moiety of a glycosaminoglycan, which has a high stability in vivo and can retain physiological activity of the protein for a prolonged period of time.

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