Glycosaminoglycan/collagen complexes and use thereof

Details Glycosaminoglycan/collagen complexes and use thereof Glycosaminoglycan/collagen complexes and use thereof

2007-06-05

2007-06-05

Wax, Robert A. (Department: 1656)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C435S283100, C435S395000

Reexamination Certificate

active

10472347

ABSTRACT:
The present invention is intended to offer a novel material which combines cell-adhesive proteins such as collagen with GAG polymers to construct an environment similar to an extracellular matrix, capable of controlling differentiation and proliferation of cells. The present invention offers a glycosaminoglycan-functionalized polymer protein composite produced by combining a cell-adhesive protein with a glycosaminoglycan-functionalized polymer obtained by incorporating a carbohydrate chain containing a structure corresponding to at least a portion of a glycosaminoglycan backbone into a vinyl polymer main chain, as well as a cell culture substrate and a material for tissue reconstruction treatments comprising the composite.

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