Glycoprotein IIB IIIA antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

549398, C07D31104, A61K 3135

Patent

active

060203625

ABSTRACT:
This invention relates to certain bicyclic compounds having a nucleus formed of two fused six membered rings, for example, benzopyran, isoquinoline, isoquinolone, tetrahydronaphthalene, dihydronaphthalene, or tetralone, substituted with both basic and acidic functionality, which are useful in inhibition of platelet aggregation.

REFERENCES:
patent: 4026907 (1977-05-01), Scott et al.
patent: 4752646 (1988-06-01), Cohen
patent: 4789750 (1988-12-01), Coffen et al.
patent: 4806661 (1989-02-01), Cohen
patent: 4853472 (1989-08-01), Coffen et al.
patent: 5039805 (1991-08-01), Alig et al.
patent: 5041453 (1991-08-01), Huang et al.
patent: 5064814 (1991-11-01), Klein et al.
Chemical Abstracts, vol. 84, N. 13, Abstract 90500z, Mar. 29, 1976, p. 566. Barxai-Beke et al.
McDowell et al., 1994, Journal American Chemical Society, vol. 116, 5077-5083.
Chemical Abstracts, vol. 75, N. 10, Abstract 74391y, Sep. 6, 1971, p. 278, Satoh et al.
Ku et al., 1993, Journal American Chemical Society, vol. 115, 8861-8862.
Blackburn et al., 1993, Annual Reports in Medicinal Chemistry, vol. 28, 79-88.
Chemical Abstracts, vol. 100, N. 17, Abstract 138973n, Apr. 23, 1984, p. 638, Otsuka Pharmaceutical Co.
Ellis, G.P., et al., Journal of Medicinal Chemistry, 1978, vol. 21, No. 11, "Benzopyrones. 14. Synthesis and Antiallergic Properties of Some N-Tetrazolylcarbosamides and Related Compounds", pp. 1120-1126.
David et al, Bull Soc. Chim Fr. vol. 130, pp. 527-534, 1993.
Kariyone et al, Chemical Abstracts, vol. 93, No. 1, Abstract No. 8018c, p. 735, Jul. 7, 1980.
Hausburg et al, Chemical Abstracts, vol. 95, No. 17, Abstract No. 150.452, p. 69, Oct. 26, 1981.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Glycoprotein IIB IIIA antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Glycoprotein IIB IIIA antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Glycoprotein IIB IIIA antagonists will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-937921

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.