Glycoprotein and gene coding therefor

Details Glycoprotein and gene coding therefor Glycoprotein and gene coding therefor

1991-08-01

1996-05-28

Furman, Keith C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

530395, C12N 1512

Patent

active

055212964

ABSTRACT:
The present invention provides a glycoprotein derived from human cell membrane, which has a molecular weight of 20 to 25 Kd as estimated by SDS polyacrylamide gel electrophoresis, and contains N-glycoside type carbohydrate chain and phosphatidylinositol, and possesses an inhibitory activity to complement-mediated cell membrane damage. The present invention further provides a gene coding for the glycoprotein, and a method for the production of the glycoprotein and the gene therefor.

REFERENCES:
patent: 4132769 (1979-01-01), Osther
patent: 4289690 (1981-09-01), Pestka et al.
patent: 4394443 (1983-07-01), Weissman et al.
patent: 4675285 (1987-06-01), Clark et al.
patent: 4800159 (1989-01-01), Mullis et al.
patent: 5135916 (1992-08-01), Sims et al.
Y. Sugita, et al., J. Biochem. 104:633-637 (1988).
I. Stefanova, et al., Mol. Immunol. 26:153-161 (1989).
N. Okada, et al., International Immunol. 1:205-208 (1989).
M. H. Holguin, et al., J. Clin. Invest. 84:7-17 (1989).
H. Okada, et al., Biochem. Biophys. Res. Comm. 162:1553-1559 (1989).
L. V. Kozlov, Immunochemistry, 10:481 (1989), Abstract No. 110:229803b.
Zalman, et al., Proc. Natl. Acad. Sci. USA 83:6975-6979 (1986).
Dahlback, et al., Biochemistry, 24:2368-2374 (1985).
DiScipio, et al., Proc. Natl. Acad. Sci. USA, 81:7298-7302 (1984).
Wood et al. 1985, Proc. Natl. Acad. Sci. 82:1585-1588.
Torczynski et al. 1984. Proc. Natl. Acad. Sci. 81:6451-6455.
Seed et al. 1987. Proc. Natl. Acad. Sci. 84:3365-3369.
Albert, B. et al. 1983. Molecular Biology of the Cell, Garland Publishing Co., N.Y., N.Y., pp. 185-196.
Matsudaira, P. 1987. J. Biol. Chem. 262(21):10035-10038.
Berent et al. 1985. Bio Techniques, May/Jun. pp. 208-220.
Maniatis et al. 1978. Cell 15:687-701.
Sugita et al. 1989. J. Biochem. 106:589-592.
Davies et al. 1989. J. Exp. Med. 170:637-654.

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