Glycopeptide antibiotics Bu-2231 A and B and process for produci

Details Glycopeptide antibiotics Bu-2231 A and B and process for produci Glycopeptide antibiotics Bu-2231 A and B and process for produci

1975-08-28

1977-09-27

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

195 80R, 424124, A61K 3574

Patent

active

040512371

ABSTRACT:
A novel water-soluble basic glycopeptide antibiotic complex designated herein as Bu-2231 is produced by fermentation of a Bu-2231-producing strain of Streptoalloteichus hindustanus. Complex Bu-2231 and two of its major components designated herein as Bu-2231 A and B are found to inhibit the growth of various Gram-positive and Gram-negative and acid-fast bacteria as well as certain plant pathogens. The complex and components Bu-2231 A and B are also useful in inhibiting the growth of various tumors in rodents, for example, Walker 256 carcinosarcoma and Lewis Lung carcinoma.

REFERENCES:
patent: 3681491 (1972-08-01), Umezawa et al.
Umezawa et al., J. Antibiotic, Ser. A., Sept. 1966, pp. 200-209.
Umezawa et al., J. Antibiotic, Ser. A., Sept. 1966, pp. 210-215.

Affiliated with

Also associated with

Rating

Glycopeptide antibiotics Bu-2231 A and B and process for produci does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Glycopeptide antibiotics Bu-2231 A and B and process for produci, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Glycopeptide antibiotics Bu-2231 A and B and process for produci will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1815127