Glycolic acid type platinum complexes

Details Glycolic acid type platinum complexes Glycolic acid type platinum complexes

1984-05-04

1986-03-18

Sneed, Helen M. S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

C07F 1500

Patent

active

045770387

ABSTRACT:
Novel platinum complexes of glycolic acid type having potent antitumor activity and high water solubility with low nephrotoxicity and a pharmaceutical composition containing one or more said compounds together with one or more carriers, diluents or excipients are provided. They can be administered parenterally to patients suffering from malignant tumors.
They are prepared by passing nitrato-platinum complexes of amines through anion exchange resins and subsequent reaction with glycolic acids.

REFERENCES:
patent: 4225529 (1980-09-01), Hydes et al.
patent: 4230631 (1980-10-01), Hydes et al.
patent: 4250189 (1981-02-01), Hydes et al.
patent: 4271085 (1981-06-01), Amundsen et al.
patent: 4359425 (1982-11-01), Totani et al.
patent: 4466924 (1984-08-01), Verbeek et al.
Chemical Abstracts 92 51723v (1980), 92 88521d (1980).
Chemical Abstracts 93 125662u (1980), 93 125663v (1980).
Chemical Abstracts 78 105899p (1973).
Chemical Abstracts 80 66593d (1973).

Affiliated with

Also associated with

Rating

Glycolic acid type platinum complexes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Glycolic acid type platinum complexes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Glycolic acid type platinum complexes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2307288