Glycineamides

Details Glycineamides Glycineamides

1977-03-23

1978-06-13

Ford, John M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260307H, 260295AM, C07D27744, C07D21375, C07D27300

Patent

active

RE0296686

ABSTRACT:
A process for the synthesis of N-aryl-3,4-dihydro-2-alkyl-4-oxo-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides by treatment of N-aryl-N'-alkyl-N'-(2'-alkoxycarbonylbenzenesulfonyl)glycineamides, useful intermediates for said process, with an alkali or alkaline earth metal hydride in a reaction-inert solvent at 50.degree.-150.degree. C., said products being antiinflammatory agents.

REFERENCES:
patent: 2676188 (1954-04-01), Bruce et al.
patent: 3591584 (1971-07-01), Lombardino
patent: 4045566 (1977-08-01), Archibald et al.
patent: 4062861 (1977-12-01), Yukinaga et al.

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